BDBM50463029 CHEMBL4241803

SMILES Cn1cc(C2=C(C(=O)N(O)C2=O)c2cn(C)c3ccccc23)c2ccccc12

InChI Key InChIKey=FXMSIIWIRRECIQ-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50463029   

TargetCyclin-dependent kinase 5 activator 1(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human CDK5/p25 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human CDK2/cyclin A using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human RIPK3 expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-33P...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of domestic porcine brain full length GSK-3alpha/beta using GS-1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human PIM1 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human haspin kinase domain expressed in bacteria using histone H3 (1 to 21 residues) peptide as substrate in presence of [g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain expressed in bacteria using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of recombinant full length human CDK9/cyclin T expressed in baculovirus infected Sf9 insect cells using YSPTSPSYSPTSPSYSPTSPSKKKK as subst...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetAurora kinase B(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463029(CHEMBL4241803)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human aurora B expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed