BDBM50463024 CHEMBL4241699

SMILES ON1C(=O)C(=C(C1=O)c1cn(CCCCCC(O)=O)c2ccccc12)c1c[nH]c2ccccc12

InChI Key InChIKey=YAPCPBJABJHWRU-UHFFFAOYSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50463024   

TargetCyclin-dependent kinase 5 activator 1(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human CDK5/p25 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase B(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human aurora B expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-A2/Cyclin-dependent kinase 2(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of full length human CDK2/cyclin A using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta/[Tau protein] kinase(Pig)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 750nMAssay Description:Inhibition of domestic porcine brain full length GSK-3alpha/beta using GS-1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human PIM1 expressed in bacteria using histone H1 as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase haspin(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant human haspin kinase domain expressed in bacteria using histone H3 (1 to 21 residues) peptide as substrate in presence of [g...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant full length human CDK9/cyclin T expressed in baculovirus infected Sf9 insect cells using YSPTSPSYSPTSPSYSPTSPSKKKK as subst...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetReceptor-interacting serine/threonine-protein kinase 3(Human)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant full length human RIPK3 expressed in baculovirus infected Sf9 insect cells using MBP as substrate in presence of [gamma-33P...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 1A(Rat)
University College Cork

Curated by ChEMBL
LigandPNGBDBM50463024(CHEMBL4241699)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of recombinant rat DYRK1A kinase domain expressed in bacteria using KKISGRLSPIMTEQ as substrate in presence of [gamma-33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed