BDBM50462940 CHEMBL4244937

SMILES [H][C@@]12CC(C=O)=C(n3cnc4ccccc34)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC=C2C[C@@H](O)CC[C@]12C

InChI Key InChIKey=BOVXPCGFUIXNNU-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462940   

Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50462940(CHEMBL4244937)
Affinity DataIC50: 291nMAssay Description:Inhibition of rat liver microsomes 5alpha-reductase1 using [1,2,6,7-3H]T as substrate measured after 60 mins by chromatographic methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 1(Rat)
Universidad Nacional Aut£Noma De M£Xico

Curated by ChEMBL
LigandPNGBDBM50462940(CHEMBL4244937)
Affinity DataIC50: 290nMAssay Description:Inhibition of rat liver microsomal SRD5A1 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed
Target3-oxo-5-alpha-steroid 4-dehydrogenase 2(Rat)
Changzhi University

Curated by ChEMBL
LigandPNGBDBM50462940(CHEMBL4244937)
Affinity DataIC50: 127nMAssay Description:Inhibition of rat liver microsomal SRD5A2 incubated for 60 mins by thin layer chromatographyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/18/2023
Entry Details
PubMed