BDBM50462571 CHEMBL4241763

SMILES CC(=O)N1CCC(CC1)Oc1nccc(C(=O)NC[C@@H](O)CNC2Cc3ccccc3C2)c1Cl

InChI Key InChIKey=VYMBYFMBBFZVJZ-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50462571   

TargetProtein arginine N-methyltransferase 5(Human)
Sun Yat-Sen University

Curated by ChEMBL
LigandPNGBDBM50462571(CHEMBL4241763)
Affinity DataIC50: 105nMAssay Description:Inhibition of human PRMT5 expressed in insect cells co-expressing His-tagged MEP50 using Ser-Gly-Arg-Gly- Lys-Gly-Gly-Lys-Gly-Leu-Gly-Lys-Gly-Gly-Ala...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed