BDBM50462367 CHEMBL4249477

SMILES COc1ccc(cc1OC)-c1nn(Cc2nc3cccc(F)c3c(=O)n2-c2c(C)cccc2C)c2ncnc(N)c12

InChI Key InChIKey=LDLLLHCVQNQXKB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50462367   

LigandPNGBDBM50462367(CHEMBL4249477)
Affinity DataIC50: 1.18E+4nMAssay Description:Inhibition of PI3Kalpha (unknown origin) using Biotin-S11S12 as substrate after 60 mins in presence of ATP by Kinase Glo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462367(CHEMBL4249477)
Affinity DataIC50: 6.96E+3nMAssay Description:Inhibition of PI3Kbeta (unknown origin) using Biotin-S11S12 as substrate after 60 mins in presence of ATP by ADPGlo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462367(CHEMBL4249477)
Affinity DataIC50: 62nMAssay Description:Inhibition of PI3Kgamma (unknown origin) using Biotin-S11S12 as substrate after 60 mins in presence of ATP by ADPGlo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
LigandPNGBDBM50462367(CHEMBL4249477)
Affinity DataIC50: 8.40nMAssay Description:Inhibition of PI3Kdelta (unknown origin) using Biotin-S11S12 as substrate after 120 mins in presence of ATP by ADPGlo luminescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed