BDBM50462328 CHEMBL4251469
SMILES CC(C)Cc1ccc(cc1)C(C)c1nc2cc(ccc2n1Cc1ccccc1Cl)-c1n[nH]c(=S)o1
InChI Key InChIKey=ZADYAZTTWZYTSD-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50462328
Affinity DataIC50: 50nMAssay Description:Inhibition of FLAP in A23187-stimulated human neutrophils assessed as reduction in 5-LO product formation preincubated for 15 mins followed by A23187...More data for this Ligand-Target Pair
Affinity DataIC50: 6.19E+3nMAssay Description:Inhibition of human LTC4 synthase expressed in HEK293 cell microsomes preincubated for 10 mins followed by LTA4-methyl ester addition and measured af...More data for this Ligand-Target Pair
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant human 5-LO expressed in Escherichia coli BL21 incubated for 15 mins prior to prewarming for 30 secs followed by CaCl2+ and ...More data for this Ligand-Target Pair
Affinity DataIC50: 420nMAssay Description:Inhibition of mPGES1 in IL-1beta-stimulated human A549 cell microsomal fractions assessed as reduction in PGE2 production preincubated for 15 mins fo...More data for this Ligand-Target Pair