BDBM50462240 CHEMBL4249195

SMILES CC(C)c1cc(C(=O)N2CCc3cc(NC(=O)CCC(=O)NO)ccc23)c(O)cc1O

InChI Key InChIKey=BKMCSLGYOKTTTN-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50462240   

TargetHistone deacetylase(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50462240(CHEMBL4249195)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of HDAC in human HeLa nuclear extract using Ac-Lys(Ac)-pNA as substrate measured after 30 mins by fluorometric analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50462240(CHEMBL4249195)
Affinity DataIC50: 1.00E+7nMAssay Description:Inhibition of human HDAC6 using RHKK(Ac) as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed
TargetHeat shock protein HSP 90-alpha(Human)
Taipei Medical University

Curated by ChEMBL
LigandPNGBDBM50462240(CHEMBL4249195)
Affinity DataIC50: 49nMAssay Description:Inhibition of FITC-geldanamycin binding to HSP90alpha (unknown origin) after 3 hrs by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/17/2020
Entry Details Article
PubMed