BDBM50460947 CHEMBL4225224

SMILES CC(C)Nc1ccc2cnn(-c3cncc(n3)-c3ccc(nc3)C(O)=O)c2c1

InChI Key InChIKey=UHPUEJXRKAJAFI-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50460947   

TargetCasein kinase II subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460947(CHEMBL4225224)
Affinity DataIC50: 297nMAssay Description:Inhibition of recombinant human full length N-terminal His6-tagged CK2alpha expressed in Sf21 insect cells using CK2tide as substrate treated for 20 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-2(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460947(CHEMBL4225224)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human PIM2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase II subunit alpha(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460947(CHEMBL4225224)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of CK2alpha in human HCT116 or human DLD1 cells assessed as decrease in AKT phosphorylation at S129 residue after 3 to 24 hrs by Western b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase pim-1(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50460947(CHEMBL4225224)
Affinity DataIC50: 3.30E+3nMAssay Description:Inhibition of human PIM1More data for this Ligand-Target Pair
In DepthDetails Article
PubMed