BDBM50459520 CHEMBL4203193

SMILES CC(C(=O)OC(C(=O)Nc1c(C)nn(c1C)-c1ccccc1)C(F)(F)F)c1c(C)[nH]c2ccccc12

InChI Key InChIKey=XUBYSXSJWYFBBX-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50459520   

TargetKallikrein-6(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459520(CHEMBL4203193)
Affinity DataIC50: 2.31E+3nMAssay Description:Inhibition of His-6-tagged human KLK6 R74G/R76Q/N132Q mutant expressed in Escherichia coli DH10 pre-incubated for 30 mins before N-Boc-FSR-AMC substr...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetTrypsin(Human)
German Cancer Research Center (Dkfz)

Curated by ChEMBL
LigandPNGBDBM50459520(CHEMBL4203193)
Affinity DataIC50: 6.10E+4nMAssay Description:Inhibition of trypsin (unknown origin) pre-incubated for 30 mins before N-Boc-FSR-AMC substrate addition and measured after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed