BDBM50458926 CHEMBL4211357

SMILES COc1ccccc1COc1cccc2onc(Nc3cccnc3)c12

InChI Key InChIKey=FUZTXRGOTFTDEX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50458926   

TargetPhosphatidylcholine:ceramide cholinephosphotransferase 2(Human)
Fudan University

Curated by ChEMBL

LigandBDBM50458926(CHEMBL4211357)Copy SMILESCopy InChI

Affinity DataIC50: 240nMAssay Description:Inhibition of human SMS2 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair

Target InfoKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMed
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TargetPhosphatidylcholine:ceramide cholinephosphotransferase 1(Human)
Fudan University

Curated by ChEMBL

LigandBDBM50458926(CHEMBL4211357)Copy SMILESCopy InChI

Affinity DataIC50: 4.80E+4nMAssay Description:Inhibition of human SMS1 using C6-NBD-ceramide and DMPC as substrate preincubated for 5 mins followed by substrate addition and measured after 30 min...More data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/16/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL