BDBM50458523 JNJ-18038683

SMILES Clc1ccc(cc1)-c1nn(Cc2ccccc2)c2CCNCCc12

InChI Key InChIKey=UKJPMZGILXATGT-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50458523   

Target5-hydroxytryptamine receptor 7(Human)
Jagiellonian University

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  3nMAssay Description:Binding affinity to 5-HT7R (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2023
Entry Details
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  6nMAssay Description:Displacement of [3H]-CT from rat 5-HT7 receptor expressed in HEK293 cells by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  6.5nMAssay Description:Displacement of [3H]5-CT from rat 5-HT7 receptor expressed in HEK293 cell membranes by radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Normandie Univ

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  6.5nMAssay Description:Antagonist activity at 5-HT1A receptor (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 2A(Human)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]-ketanserin from human 5-HT2A receptor by competitive radioligand binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/23/2022
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 7(Rat)
Janssen Research & Development

Curated by ChEMBL
LigandPNGBDBM50458523(JNJ-18038683)
Affinity DataKi:  316nMAssay Description:Displacement of [3H]5-CT from recombinant rat 5-HT7 receptor expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed