BDBM50458512 CHEMBL4215608

SMILES Fc1cccc(c1)N(C(C(=O)NC1CCCCC1)c1ccccn1)C(=O)CCl

InChI Key InChIKey=HHYJEFITGKRTJS-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50458512   

TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 35nMAssay Description:Inhibition of GSTO1-1 in human MDA-MB-231 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 21nMAssay Description:Inhibition of human recombinant GSTO1-1 incubated for 30 mins by fluorescence polarization based gel-based competitive ABPP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 21nMAssay Description:Inhibition of SE-Rh binding to human recombinant GSTO1 preincubated with compound for 30 mins followed by SE-Rh addition and measured after 1 hrs by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetGlutathione S-transferase omega-1(Human)
Monash University

Curated by ChEMBL
LigandPNGBDBM50458512(CHEMBL4215608)
Affinity DataIC50: 35nMAssay Description:Inhibition of SE-Rh binding to human recombinant GSTO1 in human MDA-MB-435 cells incubated for 1 hrs by SDS-PAGE based fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed