BDBM50457927 CHEMBL4208745

SMILES Clc1ccc2c(cc3n2cc(Cc2ccccc2)[nH]c3=O)c1

InChI Key InChIKey=XQWJECIZRPTKDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457927   

TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457927(CHEMBL4208745)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457927(CHEMBL4208745)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed