BDBM50457924 CHEMBL4208224

SMILES Cc1c2cc(Cl)ccc2n2cc(Cc3ccccc3)[nH]c(=O)c12

InChI Key InChIKey=VIRDOEJWYRVMQA-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50457924   

TargetEpidermal growth factor receptor(Human)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457924(CHEMBL4208224)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of His6-tagged EGFR (unknown origin) cytoplasmic domain expressed in baculovirus infected Sf9 insect cells after 10 mins followed by addit...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetSerine/threonine-protein kinase B-raf(Mouse)
Aljouf University

Curated by ChEMBL
LigandPNGBDBM50457924(CHEMBL4208224)
Affinity DataIC50: 100nMAssay Description:Inhibition of mouse full-length GST-tagged BRAF V600E mutant using recombinant human full length N-terminal His-tagged MEK1 as substrate preincubated...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed