BDBM50456798 CHEMBL4211708

SMILES [H][C@@]12CCc3cc(C(C)C)c(cc3[C@@]1(C)CCC[C@@]2(C)C(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccccc1OC)S(=O)(=O)N[C@H](Cc1ccccc1)C(=O)Nc1ccccc1OC

InChI Key InChIKey=JIJVWCYWVTUNJB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456798   

TargetMatrix metalloproteinase-9(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50456798(CHEMBL4211708)
Affinity DataIC50: 5.62E+4nMAssay Description:Inhibition of recombinant human MMP9 (Ala20 to Asp707 residues) expressed in CHO cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrate preincub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNeutrophil collagenase(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50456798(CHEMBL4211708)
Affinity DataIC50: 5.25E+4nMAssay Description:Inhibition of recombinant human MMP8 (Phe21 to Gly467 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Southeast University

Curated by ChEMBL
LigandPNGBDBM50456798(CHEMBL4211708)
Affinity DataIC50: 3.02E+4nMAssay Description:Inhibition of recombinant human MMP3 (Tyr18 to Cys477 residues) expressed in mouse myeloma cells using Mca-Pro-LeuGly-Leu-Dpa-Ala-Arg-NH2 as substrat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed