BDBM50456519 CHEMBL4216137

SMILES Fc1ccc(CN2C(=O)C(Oc3ccccc23)c2cccc3ccccc23)cc1

InChI Key InChIKey=ZJLYKSWVZKNQMT-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456519   

TargetGlycogen synthase kinase-3 beta(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50456519(CHEMBL4216137)
Affinity DataIC50: 5.40E+3nMAssay Description:Inhibition of recombinant human His-tagged GSK3beta using GS-2 peptide as substrate in presence of [33P]gamma-ATP after 15 mins by microbeta counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetAdenosine kinase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50456519(CHEMBL4216137)
Affinity DataIC50: 4.00E+4nMAssay Description:Inhibition of recombinant human His-tagged AK using [2,8-3H]-adenosine as substrate after 20 mins by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50456519(CHEMBL4216137)
Affinity DataKi:  5.60E+3nMAssay Description:Non-competitive inhibition of recombinant human His-tagged GSK3beta using GS-2 peptide as substrate in presence of [33P]gamma-ATP after 15 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed