BDBM50456510 CHEMBL4216522

SMILES O=C1C(Oc2cc3OCOc3cc2N1Cc1ccccc1)c1cccc2ccccc12

InChI Key InChIKey=HNIHYZBFBQHXAH-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50456510   

TargetAdenosine kinase(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50456510(CHEMBL4216522)
Affinity DataIC50: 1.36E+4nMAssay Description:Inhibition of recombinant human His-tagged AK using [2,8-3H]-adenosine as substrate after 20 mins by microbeta counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50456510(CHEMBL4216522)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of recombinant human His-tagged GSK3beta using GS-2 peptide as substrate in presence of [33P]gamma-ATP after 15 mins by microbeta counting...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGlycogen synthase kinase-3 beta(Human)
University of Siena

Curated by ChEMBL
LigandPNGBDBM50456510(CHEMBL4216522)
Affinity DataKi:  6.30E+3nMAssay Description:Non-competitive inhibition of recombinant human His-tagged GSK3beta using GS-2 peptide as substrate in presence of [33P]gamma-ATP after 15 mins by mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed