BDBM50455508 CHEMBL4205557

SMILES CCC1CN(Cc2ccccc2)c2cc(ccc2N1C(C)=O)-c1ccc(nc1)C(N)=O

InChI Key InChIKey=ZOECILBNCIOJTG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50455508   

TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455508(CHEMBL4205557)
Affinity DataIC50: 631nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y390A mutant BD1 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBromodomain-containing protein 4(Human)
University of Strathclyde

Curated by ChEMBL
LigandPNGBDBM50455508(CHEMBL4205557)
Affinity DataIC50: 63nMAssay Description:Displacement of (+)-JQ1 from 6H-Thr BRD4 Y97A mutant BD2 (unknown origin) after 30 mins by TR-FRET assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed