BDBM50455227 CHEMBL4208325

SMILES OC(=O)CCc1cc(F)c(OCc2c(ccn2-c2ccc(Cl)cc2)C(F)(F)F)c(F)c1

InChI Key InChIKey=QBQBMUDNSMUHRR-UHFFFAOYSA-N

Data  7 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50455227   

TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  80nMAssay Description:Agonist activity at recombinant human GPR120 short isoform expressed in HEK293 cells assessed as intracellular calcium flux measured for 300 secs at ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  193nMAssay Description:Agonist activity at recombinant mouse GPR120 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  69nMAssay Description:Agonist activity at recombinant human PK-tagged GPR120 long isoform expressed in CHOK1 cells co-expressing EA-tagged beta-arrestin assessed as beta-g...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Mouse)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  3.52E+3nMAssay Description:Agonist activity at mouse GPR40More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 1(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  3.34E+3nMAssay Description:Agonist activity at human GPR40More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Human)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  137nMAssay Description:Agonist activity at GPR120 in human HT-29 cells assessed as intracellular calcium fluxMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFree fatty acid receptor 4(Rat)
Janssen Research and Development

Curated by ChEMBL
LigandPNGBDBM50455227(CHEMBL4208325)
Affinity DataEC50:  713nMAssay Description:Agonist activity at recombinant rat GPR120 expressed in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed