BDBM50454857 CHEMBL4218482

SMILES [H][C@]1(NC(=O)[C@H](CC(C)C)NC(=O)CNC(=O)[C@H](CO)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCCCN)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC(=O)CSC[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O)C(C)C)C(C)C)[C@@H](C)CC

InChI Key InChIKey=OIYYXEBKWAWQQR-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50454857   

TargetLysine-specific demethylase 4C(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454857(CHEMBL4218482)
Affinity DataIC50: 154nMAssay Description:Inhibition of KDM4C (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454857(CHEMBL4218482)
Affinity DataKd:  49nMAssay Description:Binding affinity to biotinylated-KDM4A (unknown origin) at 300 nM by bio-layer interferometric methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The University of Tokyo

Curated by ChEMBL
LigandPNGBDBM50454857(CHEMBL4218482)
Affinity DataIC50: 82nMAssay Description:Inhibition of KDM4A (unknown origin) expressed in Escherichia coli using biotinylated peptide as substrate pretreated for 15 mins followed by substra...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed