BDBM50454600 CHEMBL4204424

SMILES FC(F)(F)c1ccc(Oc2cccc(CC3CCN(CC3)C(=O)Nc3cccnc3)c2)cc1

InChI Key InChIKey=FOCCPJOEDPOJRP-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50454600   

TargetFatty-acid amide hydrolase 1(Mouse)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50454600(CHEMBL4204424)
Affinity DataIC50: 12nMAssay Description:Inhibition of FAAH in mouse brain microsomes using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50454600(CHEMBL4204424)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of human FAAH expressed in baculovirus-infected High Five cells S9 fraction using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFatty-acid amide hydrolase 1 [30-579](Rat)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50454600(CHEMBL4204424)
Affinity DataIC50: 4.40nMAssay Description:Inhibition of FAAH in rat brain microsomes using OMP substrate by fluorescence based assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
University of California Davis

Curated by ChEMBL
LigandPNGBDBM50454600(CHEMBL4204424)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human recombinant soluble epoxide hydrolase expressed in baculovirus-infected High Five cells S9 fraction using CMNPC substrate by fluo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed