BDBM50454186 CHEMBL4215914

SMILES CC[C@H](CO)Nc1nc(NCc2ccccc2N)c2[nH]nc(C(C)C)c2n1

InChI Key InChIKey=QTTGJROYRLDUFU-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50454186   

TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
University of Kwazulu-Natal

Curated by ChEMBL
LigandPNGBDBM50454186(CHEMBL4215914)
Affinity DataIC50: 11nMAssay Description:Inhibition of recombinant human full length N-terminal GST-tagged CDK2 (M1 to L298 residues)/CyclinE1 (M1 to A395 residues) expressed in baculovirus ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Mizoram University

Curated by ChEMBL
LigandPNGBDBM50454186(CHEMBL4215914)
Affinity DataIC50: 11nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) expressed in Sf9 cells using histone H1 cells in presence of gamma33P-ATP by kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed