BDBM50453856 CHEMBL4212130

SMILES Cc1cc(COc2ccc(cc2)S(=O)(=O)NC2(CC(=O)NO)CN(CCC(F)(F)F)C2)c2ccccc2n1

InChI Key InChIKey=YLUIDZRKSSPLJG-UHFFFAOYSA-N

Data  1 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453856   

TargetDisintegrin and metalloproteinase domain-containing protein 17(Human)
Nestle Skin Health

Curated by ChEMBL

LigandBDBM50453856(CHEMBL4212130)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of TACE in human PBMC assessed as reduction in LPS-induced TNFalpha production incubated overnight by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
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