BDBM50453130 CHEMBL4206406

SMILES NC(=N)NCCC[C@@H]1NC(=O)[C@@H](Cc2ccccc2)NC(=O)[C@H](Cc2c[nH]cn2)NC(=O)C2(CCCCC2)NC(=O)C[C@H](NC(=O)[C@H](Cc2c[nH]c3ccccc23)NC1=O)C(N)=O

InChI Key InChIKey=YUKODIVVRQEHLF-UHFFFAOYSA-N

Data  4 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50453130   

TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataEC50:  13nMAssay Description:Agonist activity at human MC1R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation measured after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocyte-stimulating hormone receptor(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataIC50: 240nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC1R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataEC50:  33nMAssay Description:Agonist activity at human MC3R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataEC50:  10nMAssay Description:Agonist activity at human MC4R expressed in HEK293 cells assessed as induction of intracellular cAMP accumulation after 3 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 5(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataIC50: 1.00E+3nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC5R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 3(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataIC50: 11nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC3R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetMelanocortin receptor 4(Human)
University of Naples "Federico Ii

Curated by ChEMBL
LigandPNGBDBM50453130(CHEMBL4206406)
Affinity DataIC50: 160nMAssay Description:Displacement of [125I]-NDP-alpha-MSH from human MC4R expressed in HEK293 cells after 40 mins by gamma counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed