BDBM50453062 CHEMBL4207501

SMILES CCC(C(=O)N[C@@H]1CC(O)OC(=O)C1)n1c(=O)c(NC(=O)c2ccc(Nc3ccc4ccccc4c3)cc2C)cn(C(C)C)c1=O

InChI Key InChIKey=MVGWMLIGPTZNGV-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50453062   

TargetCaspase-1(Human)
Nestl�

Curated by ChEMBL
LigandPNGBDBM50453062(CHEMBL4207501)
Affinity DataIC50: 210nMAssay Description:Inhibition of caspase-1 in human THP1 cells assessed as decrease in LPS-induced IL-1beta secretion after overnight incubation by sandwich immunoassayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed