BDBM50452743 CHEMBL4208450

SMILES OC(=O)c1ccc(NC2=C\C(=N\S(=O)(=O)c3ccc4ccccc4c3)c3ccccc3C2=O)cc1

InChI Key InChIKey=BOUGCFLCXZGDOC-UHFFFAOYSA-N

Data  2 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50452743   

TargetGlycogen synthase kinase-3 beta(Human)
Peking University

Curated by ChEMBL
LigandPNGBDBM50452743(CHEMBL4208450)
Affinity DataIC50: 6.03E+3nMAssay Description:Inhibition of human GSK-3beta using YRRAAVPPSPSLSRHSSPHQS(p) EDEEE substrate peptide and [gamma-33P-ATP] incubated for 40 mins by scintillation count...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Taizhou University

Curated by ChEMBL
LigandPNGBDBM50452743(CHEMBL4208450)
Affinity DataKd:  158nMAssay Description:Binding affinity to human KEAP1 by SPR direct binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed
TargetKelch-like ECH-associated protein 1(Human)
Taizhou University

Curated by ChEMBL
LigandPNGBDBM50452743(CHEMBL4208450)
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human Keap1-Nrf2 protein-protein interaction by fluorescence polarization assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed