BDBM50452338 CHEMBL4215397

SMILES COc1ccc(cc1O)-c1c2c(n3ccc4cc(O)c(OC)cc4c13)c(=O)oc1cc(OCCCNC(N)=N)c(OC)cc21

InChI Key InChIKey=LVSQYFYXQALSGT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50452338   

TargetEpidermal growth factor receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50452338(CHEMBL4215397)
Affinity DataIC50: 39nMAssay Description:Inhibition of recombinant EGFR (unknown origin) T790M/L858R double mutant preincubated for 30 mins followed by poly (Glu-Tyr) biotinylated peptide su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Nagasaki University

Curated by ChEMBL
LigandPNGBDBM50452338(CHEMBL4215397)
Affinity DataIC50: 47nMAssay Description:Inhibition of recombinant wild type EGFR (696 to C-terminal residues) (unknown origin) preincubated for 30 mins followed by poly (Glu-Tyr) biotinylat...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed