BDBM50451458 CHEMBL4205773

SMILES NCc1cc(ccn1)-c1cc(ccc1Oc1ccc(cc1C#N)S(=O)(=O)Nc1ncns1)-c1cccc(c1)C(F)(F)F

InChI Key InChIKey=WFFJQEDUERJHMW-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451458   

TargetSodium channel protein type 9 subunit alpha(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50451458(CHEMBL4205773)Copy SMILESCopy InChI

Affinity DataIC50: 0.100nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by patch clamp electrophysiology methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL

TargetSodium channel protein type 9 subunit alpha(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50451458(CHEMBL4205773)Copy SMILESCopy InChI

Affinity DataIC50: 0.5nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by automated patchXpress electrophysiology methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
Copy BDB DOIPubMed
Copy reaction URL