BDBM50451453 CHEMBL2325603

SMILES Clc1ccc(Oc2ccc(cc2C#N)S(=O)(=O)Nc2ncns2)c(c1)-c1cccc(CN2CCC2)c1

InChI Key InChIKey=CHJONOAJXAYCSX-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50451453   

TargetSodium channel protein type 9 subunit alpha(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50451453(CHEMBL2325603)Copy SMILESCopy InChI

Affinity DataIC50: 1.60nMAssay Description:Inhibition of human Nav1.7 expressed in HEK cells by automated patchXpress electrophysiology methodMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/15/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetSodium channel protein type 9 subunit alpha(Human)
Pfizer

Curated by ChEMBL

LigandBDBM50451453(CHEMBL2325603)Copy SMILESCopy InChI

Affinity DataIC50: 1.60nMAssay Description:Inhibition of NaV1.7 ion channel (unknown origin)More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoPC cidPC sidSimilars

In Depth
Date in BDB:
8/31/2020
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL