BDBM50451276 CHEMBL4217987

SMILES OC(=O)c1cc(O)ccc1NC(=O)c1ccc(cc1)N1C(=O)c2ccccc2C1=O

InChI Key InChIKey=QRCGZVVZRATLQP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50451276   

TargetNAD-dependent protein deacylase sirtuin-6(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50451276(CHEMBL4217987)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human recombinant SIRT6 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-1(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50451276(CHEMBL4217987)
Affinity DataIC50: 4.24E+5nMAssay Description:Inhibition of human recombinant SIRT1 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNAD-dependent protein deacetylase sirtuin-2(Human)
University of Genoa

Curated by ChEMBL
LigandPNGBDBM50451276(CHEMBL4217987)
Affinity DataIC50: 3.33E+5nMAssay Description:Inhibition of human recombinant SIRT2 assessed as reduction in NAD+-dependent deacetylase activity using Arg-His-Lys-Lys(epsilon-acetyl)-AMC substrat...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed