BDBM50450549 CHEMBL4174690

SMILES Cc1ccc2nc(cc(NCC3(N)COC3)c2c1)N1CCCc2ccc(F)cc2C1

InChI Key InChIKey=BNHKKAWGNKMZHC-UHFFFAOYSA-N

Data  1 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50450549   

TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50450549(CHEMBL4174690)
Affinity DataEC50:  2nMAssay Description:Inhibition of RSV Long fusion protein assessed as protection against virus induced cytopathic effect in infected human Hep2 cells after 5 days by CCK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50450549(CHEMBL4174690)
Affinity DataIC50: 2.56E+3nMAssay Description:Inhibition of RSV Long fusion protein L138F mutant assessed as protection against virus induced cytopathic effect in infected human Hep2 cells after ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50450549(CHEMBL4174690)
Affinity DataEC50:  4nMAssay Description:Inhibition of RSV A2 fusion protein assessed as protection against virus induced cytopathic effect in infected human Hep2 cells after 5 days by CCK8 ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetFusion glycoprotein F0(Human respiratory syncytial virus)
Roche Pharma Research and Early Development

Curated by ChEMBL
LigandPNGBDBM50450549(CHEMBL4174690)
Affinity DataEC50:  2nMAssay Description:Inhibition of RSV B fusion protein assessed as protection against virus induced cytopathic effect in infected human Hep2 cells after 5 days by CCK8 a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed