BDBM50448151 CHEMBL3122226

SMILES Cn1nc(C(=O)N2CCOCC2)c2ccc(OCc3ccccn3)nc12

InChI Key InChIKey=YAOOWQWIHCHMIS-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50448151   

TargetMetabotropic glutamate receptor 1(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50448151(CHEMBL3122226)
Affinity DataIC50: 5.00E+4nMAssay Description:Negative allosteric modulation of human mGluR1 expressed in HEK293 cells assessed as inhibition of glutamate-induced calcium flux after 16 to 24 hrs ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed
TargetMetabotropic glutamate receptor 5(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50448151(CHEMBL3122226)
Affinity DataKi:  114nMAssay Description:Displacement of [3H]-MPEPy from human mGluR5 expressed in HEK293FT cells after 1 hr by liquid scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/26/2014
Entry Details Article
PubMed