BDBM50447757 CHEMBL57818

SMILES NC1=CC(=O)c2ccc(nc2C1=O)-c1ccccn1

InChI Key InChIKey=UMMNKCUSQIKSGP-UHFFFAOYSA-N

Data  2 KI  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50447757   

TargetProtein-arginine deiminase type-4(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50447757(CHEMBL57818)
Affinity DataIC50: 640nMAssay Description:Inhibition of recombinant wild-type PAD4 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-3(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50447757(CHEMBL57818)
Affinity DataIC50: 130nMAssay Description:Inhibition of recombinant wild-type PAD3 (unknown origin) using N-alpha-Benzoyl-L-arginine amide as substrate preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50447757(CHEMBL57818)
Affinity DataIC50: 320nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 15 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-1(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50447757(CHEMBL57818)
Affinity DataIC50: 950nMAssay Description:Inhibition of recombinant wild-type PAD1 (unknown origin) using N-alpha-Benzoyl-L-arginine amide as substrate preincubated for 15 mins followed by su...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-2(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50447757(CHEMBL57818)
Affinity DataKi:  8.08E+3nMAssay Description:Inhibition of recombinant wild-type PAD2 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetProtein-arginine deiminase type-4(Human)
The Scripps Research Institute-Florida

Curated by ChEMBL
LigandPNGBDBM50447757(CHEMBL57818)
Affinity DataKi:  2.01E+4nMAssay Description:Inhibition of recombinant wild-type PAD4 (unknown origin) using N-alpha-Benzoyl-L-arginine ethyl ester as substrate preincubated for 10 mins followed...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed