BDBM50447574 CHEMBL3112692

SMILES Cc1sccc1C(=O)Nc1cccnc1

InChI Key InChIKey=WUKQUARPVBIJSS-UHFFFAOYSA-N

Data  1 IC50  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50447574   

TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50447574(CHEMBL3112692)
Affinity DataKd:  3.60E+4nMAssay Description:Binding affinity to N-terminal His6-tagged/biotinylated C-terminal Avi-tagged human NAMPT (2 to 491) by SPR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetNicotinamide phosphoribosyltransferase(Human)
Genentech

Curated by ChEMBL
LigandPNGBDBM50447574(CHEMBL3112692)
Affinity DataIC50: 3.40E+4nMAssay Description:Inhibition of full length C-terminal His6-tagged human NAMPT expressed in Escherichia coli Rosetta (DE3) cells using PRPP/NAM as substrate/cofactor p...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed