BDBM50447516 CHEMBL3115900

SMILES NC(=N)c1ccc(CNC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@@H](CC2CCCCC2)NCC(O)=O)cc1

InChI Key InChIKey=DEEHPLDVAKJVIC-UHFFFAOYSA-N

Data  3 KI  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50447516   

TargetCoagulation factor XI(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of human coagulation factor 11a using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human coagulation factor 10a using S-2765 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mi...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataIC50: 260nMAssay Description:Inhibition of human APC using S-2366 as substrate preincubated for 300 seconds followed by substrate addition measured after 40 mins by spectrophotom...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetVitamin K-dependent protein C(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataKi:  100nMAssay Description:Competitive inhibition of human APC using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor XI(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataKi:  800nMAssay Description:Competitive inhibition of human coagulation factor 11a using S-2366 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCoagulation factor X(Human)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50447516(CHEMBL3115900)
Affinity DataKi:  8.00E+3nMAssay Description:Competitive inhibition of human coagulation factor 10a using S-2765 as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed