BDBM50446413 CHEMBL1668217

SMILES O=C1CC(=O)C(Cc2ccc3ccccc3c2)=CC1=O

InChI Key InChIKey=BIGJSLTZTKFRGZ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50446413   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446413(CHEMBL1668217)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 15-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446413(CHEMBL1668217)
Affinity DataIC50: 2.30E+3nMAssay Description:Inhibition of 5-LO in human PMNL using arachidonic acid as substrate preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446413(CHEMBL1668217)
Affinity DataIC50: 780nMAssay Description:Inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using arachidonic acid as substrate after 10 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446413(CHEMBL1668217)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of 12-LO in human PMNL using arachidonic acid preincubated for 15 minsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446413(CHEMBL1668217)
Affinity DataIC50: 970nMAssay Description:Competitive inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using 5 uM of arachidonic acid as substrate preincubated for 15 m...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Human)
University of Salerno

Curated by ChEMBL
LigandPNGBDBM50446413(CHEMBL1668217)
Affinity DataIC50: 310nMAssay Description:Competitive inhibition of human recombinant 5-LO expressed in Escherichia coli BL21 using 40 uM of arachidonic acid as substrate preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed