BDBM50444455 CHEBI:27924::Phenylhydrazine

SMILES c1ccc(cc1)NN

InChI Key InChIKey=HKOOXMFOFWEVGF-UHFFFAOYSA-N

Data  6 IC50

PDB links: 2 PDB IDs match this monomer.

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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50444455   

TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human IDO1 assessed as reduction in kynurenine production using L-tryptophan as substrate after 60 mins by microplate reade...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/16/2017
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: 250nMAssay Description:Inhibition of recombinant human IDO1 expressed in Escherichia coli EC538 using L-tryptophan as substrate after 1 hrMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Mouse)
University of Auckland

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: 200nMAssay Description:Inhibition of mouse IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetIndoleamine 2,3-dioxygenase 1(Human)
Bryn Mawr College

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of human IDO1 expressed in mouse LLTC cells using L-tryptophan as substrate after 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed
TargetHistone acetyltransferase KAT8(Human)
University of Groningen

Curated by ChEMBL
LigandPNGBDBM50444455(CHEBI:27924 | Phenylhydrazine)
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged KAT8 catalytic domain (125 to 458 residues) (unknown origin) expressed in Escherichia coli BL21(DE3) using SGRGK...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2020
Entry Details Article
PubMed