BDBM50444152 CHEMBL3093305

SMILES OC(=O)c1cc(ccc1N1CC[C@@H](C1)Oc1ccc(cn1)C(F)(F)F)C(F)(F)F

InChI Key InChIKey=LISONRCHUBYJHC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50444152   

TargetLipoprotein lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444152(CHEMBL3093305)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of recombinant human lipoprotein lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed
TargetEndothelial lipase(Human)
Xenon Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50444152(CHEMBL3093305)
Affinity DataIC50: 372nMAssay Description:Inhibition of recombinant human endothelial lipase using bis-BODIPY-FL C11-PC as substrate preincubated for 30 mins followed by substrate addition by...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/25/2014
Entry Details Article
PubMed