BDBM50443871 CHEMBL3091536

SMILES Cn1c(nc(cc1=O)-c1ccncn1)N1CCO[C@H](C1)c1ccc(F)cc1

InChI Key InChIKey=NKUNFNVAHJNALA-UHFFFAOYSA-N

Data  8 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50443871   

TargetGlycogen synthase kinase-3 beta(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant GSK3beta assessed as inhibition of [gamma32P]ATP after 1 hr by liquid scintillation counting in presence of prephosph...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase I isoform alpha(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of CK1 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of recombinant human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Mitsubishi Tanabe Pharma

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 2.94E+4nMAssay Description:Inhibition of recombinant human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3(Human)
Hefei University of Technology

Curated by ChEMBL
LigandPNGBDBM50443871(CHEMBL3091536)
Affinity DataIC50: 12nMAssay Description:Inhibition of human GSK3More data for this Ligand-Target Pair
In DepthDetails
PubMed