BDBM50443648 CHEMBL3093076

SMILES Fc1ncccc1[C@H](Nc1nnc(o1)-c1c[nH]c2ncccc12)C1CC1

InChI Key InChIKey=LNXSSTKGTQNUBH-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50443648   

LigandPNGBDBM50443648(CHEMBL3093076)
Affinity DataIC50: 0.690nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-T1/Cyclin-dependent kinase 9(Human)
Amgen

Curated by ChEMBL
LigandPNGBDBM50443648(CHEMBL3093076)
Affinity DataIC50: 120nMAssay Description:Inhibition of CDK9/cyclin T1 (unknown origin) using 4eBP1 ULight peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50443648(CHEMBL3093076)
Affinity DataIC50: 7.30E+3nMAssay Description:Inhibition of CDK1/cyclin B (unknown origin) by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50443648(CHEMBL3093076)
Affinity DataIC50: 490nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using ULight peptide as substrate by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50443648(CHEMBL3093076)
Affinity DataIC50: 51nMAssay Description:Inhibition of Cdc7-mediated MCM2 phosphorylation at Ser53 in human HCT116 cells after 14 hrs by immunostaining assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed