BDBM50443642 CHEMBL3093056

SMILES Fc1cc2cc(ccc2cn1)-c1nnc(NCc2ccccc2)o1

InChI Key InChIKey=CXNLSCPNUHGFQJ-UHFFFAOYSA-N

Data  3 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50443642   

TargetCell division cycle 7-related protein kinase(Human)
Amgen

Curated by ChEMBL

LigandBDBM50443642(CHEMBL3093056)Copy SMILESCopy InChI

Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Cdc7-mediated MCM2 phosphorylation at Ser53 in human HCT116 cells after 14 hrs by immunostaining assayMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

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TargetCell division cycle 7-related protein kinase/Protein DBF4 homolog A(Human)
Amgen

Curated by ChEMBL

LigandBDBM50443642(CHEMBL3093056)Copy SMILESCopy InChI

Affinity DataIC50: 10nMAssay Description:Inhibition of Cdc7/Dbf4 (unknown origin)-mediated MCM2 phosphorylation at Ser53 by protein A amplified luminescent proximity homogeneous assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
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TargetCyclin-dependent kinase 2/G1/S-specific cyclin-E1(Human)
Amgen

Curated by ChEMBL

LigandBDBM50443642(CHEMBL3093056)Copy SMILESCopy InChI

Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of CDK2/cyclin E (unknown origin) using ULight peptide as substrate by HTRF assayMore data for this Ligand-Target Pair

Target InfoPDB
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In DepthDetails Article
Copy BDB DOIPubMed
Copy reaction URL