BDBM50442164 CHEMBL2441345

SMILES Cc1cc(C)n(CC(=O)N2CCc3cc(ccc23)-c2cn(C)c3ncnc(N)c23)n1

InChI Key InChIKey=YOPJEHCJCZXQQN-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50442164   

LigandPNGBDBM50442164(CHEMBL2441345)
Affinity DataIC50: 100nMAssay Description:Inhibition of thapsigargin-induced autophosphorylation of PERK in human A549 cells preincubated for 1 hr followed by thapsigargin-induction measured ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50442164(CHEMBL2441345)
Affinity DataIC50: 1.90nMAssay Description:Inhibition of GST-tagged PERK cytoplasmic domain (536 to 1116) (unknown origin) assessed as biotinylated His6-tagged EIF2alpha phosphorylation preinc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed