BDBM50441480 CHEMBL2436581

SMILES FC(F)(F)Oc1ccc(NC(=O)N2CCC3(C2)CCN(CC3)C(=O)c2ccco2)cc1

InChI Key InChIKey=IZBDMFFHSQLDDQ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50441480   

TargetBifunctional epoxide hydrolase 2(Rat)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441480(CHEMBL2436581)
Affinity DataIC50: 9.5nMAssay Description:Inhibition of rat sEH expressed in Sf9 insect cells using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 2...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetBifunctional epoxide hydrolase 2(Human)
Toray Industries

Curated by ChEMBL
LigandPNGBDBM50441480(CHEMBL2436581)
Affinity DataIC50: 0.900nMAssay Description:Inhibition of human recombinant sEH using cyano(6-methoxy-naphthalen-2-yl)methyl trans-[(3-phenyloxiran-2-yl)methyl]carbonate after 20 to 45 mins by ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed