BDBM504413 US11040984, Compound 23

SMILES COC[C@@H]1CN(C(=O)O1)c1cc2c(Nc3cccc(Cl)c3F)ncnc2cc1OC

InChI Key InChIKey=GBWRYYKSRSTZJC-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 504413   

TargetEpidermal growth factor receptor(Human)
Medshine Discovery

US Patent
LigandPNGBDBM504413(US11040984, Compound 23)
Affinity DataIC50: 0.0380nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent

TargetEpidermal growth factor receptor [1-745,751-1210](Human)
Medshine Discovery

US Patent
LigandPNGBDBM504413(US11040984, Compound 23)
Affinity DataIC50: 0.170nMAssay Description:Buffer formulation: a buffer consisted of 50 mM HEPES (pH 7.5), 0.01% BSA, 5 mM MgCl2, 0.1 mM Orthovanadate. After the buffer was formulated, an enzy...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2021
Entry Details
Go to US Patent