BDBM50441027 CHEMBL2430159

SMILES Fc1ccc2C(=C)OC(=O)c2c1

InChI Key InChIKey=QLRMWXMGUWPSQS-UHFFFAOYSA-N

Data  3 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50441027   

TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441027(CHEMBL2430159)
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as inhibition of menthol-induced intracellular calcium influx pre...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441027(CHEMBL2430159)
Affinity DataIC50: 1.00E+5nMAssay Description:Antagonist activity at rat recombinant TRPA1 overexpressed in HEK293 cells assessed as inhibition of allyl isothiocyanate-induced intracellular calci...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily A member 1(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441027(CHEMBL2430159)
Affinity DataEC50:  3.22E+4nMAssay Description:Agonist activity at rat recombinant TRPA1 overexpressed in HEK293 cells assessed as induction of intracellular calcium influx by Fluo-4-AM dye-based ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed
TargetTransient receptor potential cation channel subfamily M member 8(Rat)
Sapienza University of Rome

Curated by ChEMBL
LigandPNGBDBM50441027(CHEMBL2430159)
Affinity DataIC50: 2.00E+5nMAssay Description:Antagonist activity at rat recombinant TRPM8 overexpressed in HEK293 cells assessed as inhibition of icilin-induced intracellular calcium influx prei...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed