BDBM50439809 CHEMBL2417574::US9227982, 11

SMILES O=C(CCc1ccncc1)N(Cc1cccs1)Cc1nc2CCOCc2c(=O)[nH]1

InChI Key InChIKey=PDQOVVDBQCANCP-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50439809   

LigandPNGBDBM50439809(CHEMBL2417574 | US9227982, 11)
Affinity DataIC50: 962nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
US Patent

LigandPNGBDBM50439809(CHEMBL2417574 | US9227982, 11)
Affinity DataIC50: 4.17E+3nMT: 2°CAssay Description:The autoparsylation activity of the TNKS 1/2 or PARP1/2 enzymes was measured by the liquid chromatography-mass spectrometry (LC/MS) detection of nico...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetProtein Wnt-3a(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50439809(CHEMBL2417574 | US9227982, 11)
Affinity DataIC50: 8.25E+3nMAssay Description:Inhibition of WNT3A signaling in HEK293 cells by luciferase reporter gene assay in presence of forskolinMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed