BDBM50439654 CHEMBL2419829::US9353075, 36

SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCOCCc1ccccc1

InChI Key InChIKey=RDNIYLLJMPKPHB-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439654   

TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50: 140nMpH: 7.4Assay Description:Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/19/2017
Entry Details
Go to US Patent

TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50: 148nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50: 140nMAssay Description:Inhibition of NAAA in Sprague-Dawley rat lung assessed as inhibition of hydrolysis of 10-cis-heptadecenoylethanolamide by UPLC/MS methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/12/2016
Entry Details Article
PubMed
TargetN-acylethanolamine-hydrolyzing acid amidase(Rat)
University of California

US Patent
LigandPNGBDBM50439654(CHEMBL2419829 | US9353075, 36)
Affinity DataIC50: 140nMAssay Description:Inhibition of Sprague Dawley rat lung native NAAA enzyme using heptadecenoylethanolamide as substrate preincubated for 30 mins followed by substrate ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/13/2014
Entry Details Article
PubMed