BDBM50439216 CHEMBL2418812

SMILES C[C@@H]1CCCN([C@@H]1C)C(=O)c1nc(Nc2ccc(Cl)cc2F)sc1C

InChI Key InChIKey=ODUIXUGXPFKQLG-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50439216   

TargetShort transient receptor potential channel 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439216(CHEMBL2418812)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 6(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439216(CHEMBL2418812)
Affinity DataIC50: 50nMAssay Description:Inhibition of human recombinant TRPC6 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439216(CHEMBL2418812)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetShort transient receptor potential channel 3(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50439216(CHEMBL2418812)
Affinity DataIC50: 250nMAssay Description:Inhibition of human recombinant TRPC3 expressed in HEK293-MSRII cells assessed as carbachol-stimulated Ca2+/Na+ influx after 10 mins by FLIPR assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed