BDBM50438189 CHEMBL2407098

SMILES CN(C)c1cccc(c1)-c1cc2c(cnc(N)c2o1)-c1cnn(c1)C1CCN(CC1)C(C)=O

InChI Key InChIKey=UHZICSPIFLEQHT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438189   

LigandPNGBDBM50438189(CHEMBL2407098)
Affinity DataIC50: 2.40E+3nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438189(CHEMBL2407098)
Affinity DataIC50: 690nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed