BDBM50438185 CHEMBL2407770

SMILES CC(=O)N1CCC(CC1)n1cc(cn1)-c1cnc(N)c2oc(cc12)-c1cccc(c1)C(N)=O

InChI Key InChIKey=XESCBULBTJHJDG-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50438185   

TargetMitogen-activated protein kinase kinase kinase 7(Human)
Osi Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50438185(CHEMBL2407770)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibition of TAK1 in human HCT116 cells assessed as inhibition of TNF-alpha-stimulated JNK phosphorylationMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50438185(CHEMBL2407770)
Affinity DataIC50: 530nMAssay Description:Inhibition of truncated TAK1-TAB1(unknown origin) using MKK7 as substrate by ALPHAScreen assay in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed